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The best result was a modest 2.6 kilograms in a short trial, and that result did not hold up in the larger, longer study designed to confirm it

In a pre-specified secondary analysis of the CONVINCE trial, we investigated the efficacy of colchicine in patients classified by achieved on-treatment high-sensitivity CRP at 28 days post-randomisation

Store the lyophilised blend at 20C, protected from moisture and light

This is the basis for oral and capsule research formats, especially in gut-focused models

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At the same time, it reduces bleeding complications and thrombocytopenia (low platelet counts) caused by anticoagulant medications like heparin and warfarin